About Us
YPBio Ltd. is the professional manufacturer of Nisin and Natamycin (Pimaricin) in China,
being able to supply high quality YP-1000 Nisin and YP-95 / YP-50 Natamycin (Pimaricin).
YP-1000 Nisin--Natural antimicrobial (protectant - bacteria inhibitor).
YP-50 Natamycin--Natural antimicrobial (protectant - yeast and mould inhibitor).
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YP-1000 Nisin is a kind of naturally antibacterial peptide. It has been researched and produced by YPBio utilizing bio-tech means through many years study. And our more advanced R&D of YP-1000 Nisin is honorably assigned as a key-tech of program of the Tenth Five-year-plan of China in 2002. (It is the highest grade high-tech in China.)
YP-1000 Nisin is a natural preservative & antimicrobial agent with high efficiency for foods and pharmaceuticals.
YP-1000 Nisin is a polypeptide produced by Lactococcus lactis. It consists of 34 amino acids. It is a natural antimicrobial agent and used as a natural food preservative with high efficiency, nontoxic, no harm to human and is free from side effects. Nisin is deemed to be a GRAS (Generally Recognized as Safe) substance in USA , and is assigned to be the number E-234£natural preservative in European Union .
Structure & Appearance:
Structure:
C.A.S. number1414 - 45 -5
Chemical formula : C143H228O37N42S7
Formula weight : 3348
Antimicrobial property:
YP-1000 Nisin possesses anti-microbial activity against a wide range of
Gram-positive bacteria, particularly those that produce spores. Such as ALICYCLOBACILLUS SPP ¡¢
BACILLUS SPP¡¢CLOSTRIDIUM SPP¡¢DESULFOTOMACULUM SPP¡¢ENTEROCOCCUS SPP¡¢LACTOBACILLUS SPP¡¢ LEUCONOSTOC SPP¡¢LISTERIA SPP¡¢ MICROCOCCUS SPP¡¢ PEDIOCOCCUS SPP¡¢STAPHYLOCOCCUS SPP ¡¢SPOROLACTOBACILLUS SPP ¡
It inhibits strains of the pathogen, such as Clostridium botulinum, Staphylococcus aureus, Streptococcus haemolyticus, Listeria monocytogenes, Bacillus stearothermophilus, Bacillus subtilis, Bacillus coagulans, Bacillus cereus, Bacillus Lichiniformis, Clostridium sporogenes, Clostridium bifermentum, Clostridium perfringens, Clostridium pasteurianum, Clostridium Thermosaccharohyticum, Clostridium tyobutyicum, Streptococcus agalactia, Streptococcus pyogenes, Micrococcus luteus, Lactobacillus breuis, actobacillus bulgaricus, Lactobacillus casei, Lacftobacuillus plantarum, Lzactobacillus buchneri, Leuconostoc mesenteroides, Leuconostoc oenos, Pedococcus acidlactici, Pedococcus damnosus, Pedococcus pentosaceus, Enterococcus spp, ....and so on.
YP-1000 Nisin is also able to inhibit Gram-negative bacteria e.g. Salmonella spp, Escherichia coli, Pseudomonsa spp, Bacteroides spp, Actinobacillus spp, Klebsiella spp.
Safety:
YP-1000 Nisin is a natural preservative for foods. It was approved as a natural food preservative by most major food producing countries as well as with the Food and Agriculture Organization/World Health Organization (FAO/WHO) and the European Union.
It is designated as a GRAS substance in the USA and has specific approval in , among others , EU , Australasia and Macrocosm .
The European Union has assigned Nisin to be the number E234. Elsewhere it may be included on the product label as 'Nisin preservative', 'permitted preservative' or 'natural preservative', depending on local regulations.
Physics & Chemistry Character and Quota Character:
Physics & Chemistry Quota:
Form: Powder
Sodium Chloride: ¡Ý 70 %
Moisture: < 3 %
pH of 10% aqueous solution: 3.0-3.5
Heavy metals: < 10 ppm
Arsenic (As): < 0.1 ppm
YP-1000 Nisin activity: ¡Ý 1000 IU/mg
Microbiological Count: < 10 cfu/g
Pathogen : ABSENT
Application:
As a food preservative , YP-1000 Nisin is used in a number of foods:
1.Dairy products 2. Canned foods 3. Plant protein foods 4. Meat product 5. Beer& r
