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Onecoup Lifescience
 
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Pharmaceutical Chemicals


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Hyaluronic acid

Hyaluronic acid (abbreviated as HA, also called sodium hyaluronate) is a straight chain macromolecular mucopolysaccharide composed of repeat disaccharide units of glucuronicacid and N-acetylglucosamine, which exists in the connective tissues of human and animals, including extra cellular space of human and animal tissues, vitreums, umbilical cords, skin joints synovia and cockscomb. Its molecular weight ranges from several ten thousand to several million. Its solution has extraordinary quality of keeping moisture, high viscoelasticity and lubricity. The applications are cosmetics, pharmacy and health and beauty food. Cosmetic grade HA HA is also called Natural Moisturizing Factor (NMF) due to its outstanding moisture keeping feature. It is the best component used in cosmetics for moisture keeping in the nature. Macromolecular HA helps form an air permeable thin layer and keep the skin smooth and moist, and protect the skin from bacteria, dust and ultraviolet ray, while micromolecule HA penetrates into corium, and slightly enlarge blood capillaries, speed blood circulation, improve intermediary metabolism and nourishment absorbing ability of skin, eliminate wrinkles, increase skin's elasticity and postpone aging. HA can also further hyperplasia of epidermis cells, clean oxygen free radicals, prevent and cure skin breach. Its solution has high viscosity thickening water phase. Creams made of HA by emulsifying with oil are emulsification stable, equal and fine. Meanwhile HA is compatible in different cosmetics such as creams, lotions. cosmetic water, essence, milk for face washing, liquid for bath, agents for hair washing and protection,mousse, lip stick. The dosage about 0.05%-0.5% Medical grade HA HA keeps moisture, maintain intercellular space, regulate osmotic pressure, moisturize and help cure cells. The carboxyl and hydroxyl in HA molecules come into being intramolecular and intermolecular hydrogen bonds, which can collect moisture 400 times itself. High concentrate HA solution has high viscoelasticity due to its intermolecular three grade reticular formation. As main part of intercellular substance, HA regulates the exchange of intracellular and intercellular electrolytes, filters physical and molecule information. Macromolecule HA restrain the transfer, proliferation and differentiation of cells, however micromolecule HA is helpful to those actions. Based on the above features, HA is applied in surgeries of eyes, osteoarthritis , and rheumatoidarthritis. Also it is used in eye drops and surgery recovery. With the development of pharmaceutical technology, hyaluronic acid will be used in more applications. Food grade HA With low concentration of HA, the skin becomes coarse and wrinkle, which also leads to arthritis, arteriosclerosis, plus disorder and brain atrophy, that is premature ageing. Oral HA solves these symptoms and keep human body young and full of energy.

Product ID / Sku: OC-CN/071127HA
  
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